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KMID : 0359320110510020171
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Korean Journal of Veterinary Research
2011 Volume.51 No. 2 p.171 ~ p.175
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Malignant Sertoli cell tumor in Shih Tzu dog
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강상철:Kang Sang-Chul
양형석:Yang Hyoung-Seok/정지열:Jung Ji-Youl/정은혜:Jung Eun-Hye/이희천:Lee Hee-Chun/황의경:Hwang Eui-Kyung/김재훈:Kim Jae-Hoon
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Abstract
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Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.
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KEYWORD
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cryptorchid testis, dog, immunohistochemistry, malignant Sertoli cell tumor
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